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货号： bs-12032R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12032R-PE-Cy7
- 英文名称
- Anti-GRASP/PE-Cy7
- 中文名称
- PE-Cy7标记的一般受体磷酸肌醇相关支架蛋白1抗体
- 别 名
- General Receptor for phosphoinositides 1; GRASP1; General receptor for phosphoinositides 1-associated scaffold protein; GRASP; GRASP_HUMAN; GRP1 (general receptor for phosphoinositides 1) associated scaffold protein; GRP1 associated scaffold protein; GRP1-associated scaffold protein; Tamalin.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 神经生物学 细胞膜受体 细胞骨架
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 45kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GRASP/General Receptor for phosphoinositides 1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a protein that functions as a molecular scaffold, linking receptors, including group 1 metabotropic glutamate receptors, to neuronal proteins. The encoded protein contains conserved domains, including a leucine zipper sequence, PDZ domain and a C-terminal PDZ-binding motif. Alternately spliced transcript variants have been observed for this gene.[provided by RefSeq, Dec 2012]
Function:
Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses.
Subunit:
Heteromer. Composed of GRASP, PSCD2 and at least one GRM1. Also interacts with PSCD3, GRM2, GRM3 and GRM5
Subcellular Location:
Cytoplasm, perinuclear region (By similarity). Cell membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Cell junction, synapse, postsynaptic cell membrane (By similarity). Note=Localized at postsynaptic membranes.
Similarity:
Contains 1 PDZ (DHR) domain.
Database links:Entrez Gene: 160622Human
Entrez Gene: 56149Mouse
Entrez Gene: 192254Rat
Omim: 612027Human
SwissProt: Q7Z6J2Human
SwissProt: Q9JJA9Mouse
SwissProt: Q8R4T5Rat
Unigene: 407202Human
Unigene: 621295Human
Unigene: 276573Mouse
Unigene: 82758Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.