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货号： bs-12042R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12042R-PE-Cy7
- 英文名称
- Anti-T2R60/PE-Cy7
- 中文名称
- PE-Cy7标记的味觉受体蛋白家族2亚基60抗体
- 别 名
- T2R56; TAS2R60; Taste receptor type 2 member 60; T2R60_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 信号转导 细胞膜受体 G蛋白偶联受体 G蛋白信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Bee,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 36kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human T2R60
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
T2R60 is a 318 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor T2R family. T2R60 acts as a receptor that may play a role in the perception of bitterness, and is also thought to be involved in sensing the chemical composition of gastrointestinal content. As a gustducin-linked receptor, the activity of T2R60 may stimulate G alpha (alpha gustducin), mediate PLC beta 2 activation and lead to the gating of TRPM5. While expressed in subsets of taste receptor cells of the tongue and palate epithelium, T2R60 is found exclusively in gustducin-positive cells. The gene that encodes T2R60 contains 957 bases and maps to human chromosome 7q35. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
Function:
T2R60 may play a role in the perception of bitterness and is gustducin-linked. It is expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.
Subcellular Location:
Cell Membrane; Multi-pass membrane protein.
Tissue Specificity:
Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.
Similarity:
Belongs to the G-protein coupled receptor T2R family.
Database links:Entrez Gene: 338398Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.