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货号: bs-12017R-PE-Cy7 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-12017R-PE-Cy7
- 英文名称
- Anti-GPR88/PE-Cy7
- 中文名称
- PE-Cy7标记的G蛋白偶联受体88抗体
- 别 名
- G protein coupled receptor 88; G protein-coupled receptor 88; G-protein coupled receptor 88; Probable G protein coupled receptor 88; STRG; Striatum specific G protein coupled receptor; GPR88_HUMAN; GPCR88.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 信号转导 细胞膜受体 G蛋白偶联受体 G蛋白信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 38kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human G protein coupled receptor 88
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR88 (G protein-coupled receptor 88), also known as STRG, is a 384 amino acid multi-pass membrane protein that localizes to the cell membrane and belongs to the G protein coupled receptor family. Expressed exclusively in striatum, GPR88 functions as an orphan receptor that may be involved in signaling pathways throughout the cell. Human GPR88 shares 95% sequence identity with its rat counterpart, suggesting a conserved role between species.
Function:
An orphan receptor belonging to the G-protein coupled receptor 1 family, GPR88 is expressed almost exclusively in striatum.
Subcellular Location:
Cell Membrane; Multi-pass membrane protein
Tissue Specificity:
Expressed almost exclusively in striatum.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
Database links:Entrez Gene: 54112 Human
Entrez Gene: 64378 Mouse
Entrez Gene: 64443 Rat
Omim: 607468 Human
SwissProt: Q9GZN0 Human
SwissProt: Q9EPB7 Mouse
SwissProt: Q9ESP4 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.