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货号： bs-11915R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11915R-PE-Cy7
- 英文名称
- Anti-NRSN1/PE-Cy7
- 中文名称
- PE-Cy7标记的神经囊泡膜蛋白1抗体
- 别 名
- Neurensin-1; Neuro-p24; NRSN1; NRSN1_HUMAN; p24; Vesicular membrane protein of 24 kDa; Vesicular membrane protein p24; VMP.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 发育生物学 神经生物学 信号转导 细胞膜蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Horse, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 21kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NRSN1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Neurensin-1 (NRSN1), also designated Vesicular membrane protein of 24 kDa (VMP) or Neuro-p24, is a 195 amino acid multi-pass membrane protein belonging to the VMP family that is involved in the transport of neural organelle transport and in the transduction of nerve signals or in nerve growth. Expressed solely in brain, Neurensin-1 is also thought to play a role in neurite extension. The gene encoding Neurensin-2 maps to human chromosome 6, which contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda, Parkinsons disease, Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6.
Function:
May play an important role in neural organelle transport, and in transduction of nerve signals or in nerve growth. May play a role in neurite extension.
Subcellular Location:
Membrane. Localizes mainly to neurites.
Tissue Specificity:
Expressed in brain. Not detectable in other tissues tested.
Similarity:
Belongs to the VMP family.
Database links:Entrez Gene: 140767 Human
Entrez Gene: 22360 Mouse
Entrez Gene: 291129 Rat
SwissProt: Q8IZ57 Human
SwissProt: P97799 Mouse
Unigene: 726270 Human
Unigene: 4766 Mouse
Unigene: 225156 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.