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货号： bs-11921R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11921R-PE-Cy7
- 英文名称
- Anti-GATAD1/PE-Cy7
- 中文名称
- PE-Cy7标记的眼发育相关基因蛋白ODAG抗体
- 别 名
- ODAG; GATA zinc finger domain containing 1; Ocular development associated gene; GATA zinc finger domain-containing protein 1; ocular development-associated gene protein; GATAD1 protein; ocular development associated; ODAG; RG083M05.2; tcag7.279; GATD1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 信号转导 生长因子和激素 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 29kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GATAD1/ODAG
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene contains a zinc finger at the N-terminus, and is thought to bind to a histone modification site that regulates gene expression. Mutations in this gene have been associated with autosomal recessive dilated cardiomyopathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]
Function:
ODAG (Ocular development-associated gene), a novel transcription factor located on chromosome 7, encodes a protein that may play a role in eye development. mRNA profiling in multiple human tissue indicates that ODAG is expressed in human CD56+ NK cells and thyroid tissue.
Subunit:
Component of a chromatin complex, at least composed of KDM5A, GATAD1 and EMSY.
Subcellular Location:
Nuclear
Tissue Specificity:
Ubiquitously expressed among various tissue types. Expressed in left ventricular myocytes.
DISEASE:
Defects in GATAD1 are the cause of cardiomyopathy, dilated type 2B (CMD2B) [MIM:614672]. CMD2B is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
Similarity:
Contains 1 GATA-type zinc finger.
Database links:Entrez Gene: 57798Human
Entrez Gene: 67210Mouse
SwissProt: Q8N5Y5Human
SwissProt: Q8WUU5Human
SwissProt: Q3TS14Mouse
SwissProt: Q8VCQ2Mouse
SwissProt: Q920S3Mouse
SwissProt: Q9CSG2Mouse
Unigene: 21145Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.