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货号: bs-11878R-PE-Cy7 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-11878R-PE-Cy7
- 英文名称
- Anti-LRRTM4/PE-Cy7
- 中文名称
- PE-Cy7标记的富含亮氨酸重复跨膜神经元蛋白4抗体
- 别 名
- Leucine rich repeat transmembrane neuronal 4; Leucine rich repeat transmembrane neuronal 4 protein; Leucine rich repeat transmembrane neuronal protein 4; Leucine-rich repeat transmembrane neuronal 4 protein; Leucine-rich repeat transmembrane neuronal protein 4; LRRT4_HUMAN; Lrrtm4.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 发育生物学 神经生物学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 64kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human LRRTM4
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The LRRTM protein family plays a role in the regulation of various cellular events during nervous system development. Localizing predominantly to the nervous system, LRRTM family members are known to exhibit synaptogenic activity. LRRTM4 (leucine-rich repeat transmembrane neuronal protein 4) is a 590 amino acid member of the LRRTM protein family. Expressed in neuronal tissues, LRRTM4 may play a role in the development and maintenance of the vertebrate nervous system. A single-pass type I membrane protein, LRRTM4 contains 10 LRR repeats. LRRTM4 is expressed as two isoforms produced by alternative splicing.
Function:
May play a role in the development and maintenance of the vertebrate nervous system.
Subcellular Location:
Cell membrane; Single-pass type I membrane protein (By similarity). Cell junction, synapse, postsynaptic cell membrane; Single-pass type I membrane protein
Tissue Specificity:
Expressed in neuronal tissues.
Similarity:
Belongs to the LRRTM family.
Contains 10 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.
Database links:Entrez Gene: 80059 Human
Entrez Gene: 243499 Mouse
Entrez Gene: 500219 Rat
Omim: 610870 Human
SwissProt: Q86VH4 Human
SwissProt: Q80XG9 Mouse
Unigene: 285782 Human
Unigene: 473274 Mouse
Unigene: 483425 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.