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货号： bs-11884R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11884R-PE-Cy7
- 英文名称
- Anti-NEUROD6/PE-Cy7
- 中文名称
- PE-Cy7标记的神经细胞分化因子6抗体
- 别 名
- MATH2/NEUROD6; MATH2 / NEUROD6; Atoh 2; Atoh2; Atonal homolog 2; Atonal protein homolog 2; Atonal protein homolog2; bHLH a2 antibodybHLHa 2; bHLHa2; Class A basic helix-loop-helix protein 2; Helix loop helix protein mATH 2; Helix loop helix protein mATH2; MATH 2; Math2; NDF 6; NDF6; NDF6_HUMAN; Neuro D6; NeuroD6; Neurogenic differentiation 6; Neurogenic differentiation factor 6; Nex 1 antibodyNex 1m; Nex; Nex1; Nex1 m; Nex1m; Protein atonal homolog 2; Protein atonal homolog2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 细胞分化 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow, Monkey,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 38kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MATH2/NEUROD6
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The Drosophila atonal gene produces a protein with basic helix loop helix (bHLH) domains that plays an essential role in the development of the Drosophila nervous system. Mammalian atonal homolog 2 (MATH-2) is a helix-loop-helix (HLH) transcription factor that is structurally homologous to the product of Drosophila atonal gene. MATH-2 is a 337 amino acid protein with an atonal-related basic HLH domain. In mice, expression of MATH-2 takes place by embryonic day 11.5 and initially localizes to the wall of brain vesicles and in the spinal cord. It is expressed in the cortical plate and the mantle layer in the developing central nervous system, and is limited to the nervous system in adults. Adult mouse cerebrums produce a high level of MATH-2 RNA with lower levels in other neuronal tissues. Research studies suggest that MATH-2 may function as a trans-acting factor involved in the development and maintenance of the mammalian nervous system.
Function:
Activates E box-dependent transcription in collaboration with TCF3/E47. May be a trans-acting factor involved in the development and maintenance of the mammalian nervous system. Transactivates the promoter of its own gene.
Subunit:
Efficient DNA binding requires dimerization with another bHLH protein
Subcellular Location:
Nucleus.
Similarity:
Contains 1 basic helix-loop-helix (bHLH) domain.
Database links:Entrez Gene: 63974Human
Entrez Gene: 11922Mouse
Entrez Gene: 500137Rat
Entrez Gene: 540464Cow
Omim: 611513Human
SwissProt: Q08DI0Cow
SwissProt: Q96NK8Human
SwissProt: P48986Mouse
Unigene: 45152Human
Unigene: 5106Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.