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货号： bs-11891R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11891R-PE-Cy7
- 英文名称
- Anti-Myotrophin/PE-Cy7
- 中文名称
- PE-Cy7标记的颗粒细胞分化蛋白抗体
- 别 名
- FLJ31098; FLJ99857; GCDP; Granule cell differentiation protein; MTPN; MTPN_HUMAN; Myotrophin; Protein V 1; Protein V-1; V 1; MTPN_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 心血管 细胞生物 神经生物学 细胞分化
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 13kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from humam Myotrophin/GCDP
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3 end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease. [provided by RefSeq, Jul 2008]
Function:
Potential role in cerebellar morphogenesis. May function in differentiation of cerebellar neurons, particularly of granule cells. Seems to be associated with cardiac hypertrophy.
Subunit:
Interacts with RELA (By similarity). Interacts with the heterodimer formed by CAPZA1 and CAPZB.
Subcellular Location:
Cytoplasm (Probable). Nucleus (By similarity). Cytoplasm, perinuclear region (By similarity).
Tissue Specificity:
Ubiquitous.
Similarity:
Belongs to the myotrophin family.
Contains 3 ANK repeats.
Database links:Entrez Gene: 136319Human
Entrez Gene: 14489Mouse
Entrez Gene: 79215Rat
Entrez Gene: 403487Dog
Omim: 606484Human
SwissProt: Q863Z4Dog
SwissProt: P58546Human
SwissProt: P62774Mouse
SwissProt: P62775Rat
SwissProt: Q7T2B9Zebrafish
Unigene: 602015Human
Unigene: 182746Mouse
Unigene: 3239Rat
Unigene: 75187Zebrafish
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.