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货号： bs-11853R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11853R-PE-Cy7
- 英文名称
- Anti-HMX2/PE-Cy7
- 中文名称
- PE-Cy7标记的同源盒蛋白H6亚型2抗体
- 别 名
- H6 family homeo box 2; H6 family homeobox 2; H6 homeo box 2; H6L; HMX 2; HMX2 ; HMX2_HUMAN ; Homeo box (H6 family) 2; Homeo box protein H6 family member 2; Homeobox (H6 family) 2 ; Homeobox protein H6 family member 2; Homeobox protein HMX2; Nkx5 2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 信号转导 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Chicken, Dog, Pig, Cow, Horse, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 30kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human HMX2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and the control of gene expression. HMX2 (H6 family homeobox 2), also known as H6L or Nkx5-2, is a 273 amino acid nuclear protein that belongs to the HMX homeobox family and contains one homeobox DNA-binding domain. HMX2 functions as a transcription factor that assists in specification of neuronal cell types and is essential for proper development of hypothalamus and inner ear. Hemizygous deletions of the gene encoding HMX2 are thought to lead to vestibular dysfunction, inner ear malformations and congenital sensorineural hearing loss.
Function:
Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the HMX homeobox family.
Contains 1 homeobox DNA-binding domain.
Database links:
UniProtKB/Swiss-Prot: A2RU54.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.