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货号： bs-0791R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-0791R-PE-Cy7
- 英文名称
- Anti-CGRP/PE-Cy7
- 中文名称
- PE-Cy7标记的降钙素基因相关肽2抗体
- 别 名
- CGRP-I + CGRP-II; CGRP-1/2; Procalcitonin; Beta type CGRP; CALC2; CALCB; Calcitonin 1; Calcitonin 2; Calcitonin gene related peptide; Calcitonin gene related peptide II; Calcitonin related polypeptide beta; CGRP; CGRP II; CGRP2; CT; Calcitonin/calcitonin related polypeptide alpha; Katacalcin; MGC126648; CALCA_HUMAN; CALCB_HUMAN; Calcitonin gene-related peptide 2; Beta-type CGRP; Beta-CGRP; Calcitonin gene-related peptide II; CGRP-II; CGRP-I.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 神经生物学 生长因子和激素
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Pig, Cow,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 3.8kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CGRP
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009]
Function:
CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role.
Subcellular Location:
Secreted.
Similarity:
Belongs to the calcitonin family.
Database links:Entrez Gene: 796 Human
Entrez Gene: 797 Human
Entrez Gene: 116903 Mouse
Entrez Gene: 12310 Mouse
Entrez Gene: 171519 Rat
Entrez Gene: 24241 Rat
Omim: 114130 Human
Omim: 114160 Human
SwissProt: P01258 Human
SwissProt: P06881 Human
SwissProt: P10092 Human
SwissProt: P70160 Mouse
SwissProt: Q99JA0 Mouse
SwissProt: P01256 Rat
SwissProt: P01257 Rat
Unigene: 37058 Human
Unigene: 534305 Human
Unigene: 273838 Mouse
Unigene: 4361 Mouse
Unigene: 88080 Rat
Unigene: 90085 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CGRP活性多肽，有37个氨基酸组成，具有多种生理功能，其药理作用已受到广泛重视.
CGRP （又称CGRP-1/2或CGRPa/β）广泛分布于神经系统的一种神经肽，在外周及脊髓参与伤害性信息的传递及痛敏化的形成，并与P物质、兴奋性氨基酸、辣椒素1型受体、趋化因子、激活素、大麻素受体、阿片受体、神经生长因子、血管活性肠肽、5-羟色胺、糖皮质激素等生物活性物质或受体在痛觉调制过程中存在相互影响。