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货号： bs-0792R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-0792R-PE-Cy7
- 英文名称
- Anti-Maspin/PE-Cy7
- 中文名称
- PE-Cy7标记的抑癌基因抗体
- 别 名
- mammary serine proteinase inhibitor; Maspin; Ovalbumin; PI-5; PI5; Protease inhibitor 5; Serine (or cysteine) peptidase inhibitor, clade B, member 5; Serpin B5; serpin peptidase inhibitor; Serpin peptidase inhibitor, clade B (ovalbumin), member 5; SERPINB5; SPB5_HUMAN; Spi5; Spi7.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 42kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Maspin
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The Maspin protein is a sour depressant of nenzyme of a kind of silk ammonia that represses the tumor, is the sour depressant of protei nenzyme one member within super household of the silk ammonia, it is in repress the tumor growth and transfer exertive certain function.
Function:
Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
Subunit:
Interacts with IRF6.
Subcellular Location:
Secreted, extracellular space.
Tissue Specificity:
Normal mammary epithelial cells.
Similarity:
Belongs to the serpin family. Ov-serpin subfamily.
Database links:Entrez Gene: 5268 Human
Entrez Gene: 20724 Mouse
Entrez Gene: 116589 Rat
Omim: 154790 Human
SwissProt: P36952 Human
SwissProt: P70124 Mouse
SwissProt: P70564 Rat
Unigene: 55279 Human
Unigene: 268618 Mouse
Unigene: 25752 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Maspin蛋白是一种抑制肿瘤的丝氨酸蛋白酶抑制剂, 是丝氨酸蛋白酶抑制剂超家族中的一员，它在抑制肿瘤生长和转移中发挥一定作用。