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货号： bs-0337R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-0337R-PE-Cy7
- 英文名称
- Anti-Myelin Protein Zero/PE-Cy7
- 中文名称
- PE-Cy7标记的外周髓磷脂P0蛋白/P0蛋白抗体
- 别 名
- peripheral myelin prothein Zero; MPZ; MPP; Myelin P0 protein; CHM; CMT1; CMT1B; DSS; MYELIN GLYCOPROTEIN P-ZERO; MYELIN PROTEIN PERIPHERAL; Myelin protein zero; P0; MYP0_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 神经生物学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 24kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human P0 protein (209-228aa)
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Myelin protein-zero is the major structural protein of peripheral myelin, accounting for more than 50% of the protein present in the sheath of peripheral nerves. Expression of the gene encoding Myelin protein-zero (MPZ) is restricted to Schwann cells; MPZ is not found in the CNS. An integral membrane glycoprotein of ~28kDa, Myelin protein-zero is thought to link adjacent lamellae and thereby stabilize the myelin assembly. The other 3 major components of myelin are myelin basic protein, myelin proteolipid protein and myelin-associated glycoprotein.
Subunit:
Homodimer and homotetramer.
Subcellular Location:
Cell membrane; Single-pass type I membrane protein.
Tissue Specificity:
Found only in peripheral nervous system Schwann cells.
Similarity:
Belongs to the myelin P0 protein family.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Database links:Entrez Gene: 4359 Human
Entrez Gene: 17528 Mouse
Omim: 159440 Human
SwissProt: P25189 Human
SwissProt: P27573 Mouse
Unigene: 591486 Human
Unigene: 93883 Human
Unigene: 9986 Mouse
UniProtKB/Swiss-Prot: P25189.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
成熟的周围神经系统髓鞘主要的蛋白为P0蛋白，分子量28KDa，它具有单个跨膜区，是IgG超家族的成员之一。