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货号： bs-1052R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-1052R-PE-Cy7
- 英文名称
- Anti-NAP1L1/PE-Cy7
- 中文名称
- PE-Cy7标记的核小体组装蛋白1抗体
- 别 名
- NAP1L; FLJ16112; hNRP; HSP22 like protein interacting protein; MGC23410; MGC8688; NAP 1; NAP 1 related protein; NAP 1L; NAP-1 related protein; NAP-1-related protein; NAP1; NAP1 L1; NAP1 related protein; Nap1l1; NAP1L1 protein; NP1L1_HUMAN; NRP; Nucleosome assembly protein 1 like 1; Nucleosome assembly protein 1-like 1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 染色质和核信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 44kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NAP1L1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a member of the nucleosome assembly protein (NAP) family. This protein participates in DNA replication and may play a role in modulating chromatin formation and contribute to the regulation of cell proliferation. The binding of sequence-specific DNA binding proteins to human nucleosome assembly protein 1 may be an important step contributing to the activation of transcription. May be involved in modulating chromatin formation and contribute to regulation of cell proliferation.
Function:
May be involved in modulating chromatin formation and contribute to regulation of cell proliferation.
Subcellular Location:
Nucleus. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Tissue Specificity:
Ubiquitously expressed.
Post-translational modifications:
Polyglutamylated by TTLL4, a modification that occurs exclusively on glutamate residues and results in polyglutamate chains on the gamma-carboxyl group. Some residues may also be monoglycylated but not polyglycylated due to the absence of functional TTLL10 in human.
Similarity:
Belongs to the nucleosome assembly protein (NAP) family.
Database links:Entrez Gene: 4673 Human
Entrez Gene: 53605 Mouse
Entrez Gene: 89825 Rat
Omim: 164060 Human
SwissProt: P55209 Human
SwissProt: P28656 Mouse
SwissProt: Q9Z2G8 Rat
Unigene: 524599 Human
Unigene: 695185 Human
Unigene: 290407 Mouse
Unigene: 162938 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
核小体组装蛋白1（NAP-1） 作为核心组蛋白的分子伴蛋白,在进化过程中是相当保守的.它通过帮助核心组蛋白沉积到DNA上来促进核小体的组装.而大量研究表明,酵母和动物中的NAP类似蛋白除了具有核小体组装能力以外,还有其它多种功能