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货号： bs-0075R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-0075R-PE-Cy7
- 英文名称
- Anti-Nociceptin/PE-Cy7
- 中文名称
- PE-Cy7标记的孤菲肽/痛敏肽抗体
- 别 名
- PNOC; N/OFQ; N23K; N23K/N27K; Nociceptin, included; Npnc1; OFQ; OFQ/N; Orphanin FQ; PPNOC; prepronociceptin; Propronociceptin; PNOC_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 心血管 神经生物学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 20kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Nociceptin (130-146aa)
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Nociceptin (PNOC) is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development. Expressed predominantly in the spinal cord and brain, being more abundant in the hypothalamus and striatum. Also found in small amounts in ovary. Belongs to the opioid neuropeptide precursor family.
Function:
Nociceptin is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development (By similarity).
Subcellular Location:
Secreted.
Tissue Specificity:
Predominantly in the brain and spinal cord.
Similarity:
Belongs to the opioid neuropeptide precursor family.
Database links:Entrez Gene: 5368 Human
Entrez Gene: 18155 Mouse
Entrez Gene: 25516 Rat
Omim: 601459 Human
SwissProt: Q13519 Human
SwissProt: Q64387 Mouse
SwissProt: Q62923 Rat
Unigene: 88218 Human
Unigene: 16347 Mouse
Unigene: 486163 Mouse
Unigene: 87935 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
孤菲肽（Nociceptin又称为Orphanin FQ; PPNOC; ORL1）是新发现的一种神经肽，由17个氨基酸组成，又称痛敏肽。消化道肿瘤病人的血浆中OFQ含量明显高于对照组，尤以结肠癌、胃癌最为明显。