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货号： bs-1510R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-1510R-PE-Cy7
- 英文名称
- Anti-AATK/PE-Cy7
- 中文名称
- PE-Cy7标记的AATK细胞凋亡关联酪氨酸激酶抗体
- 别 名
- AATK; AATYK; AATYK1; Apoptosis associated tyrosine kinase; Apoptosis-associated tyrosine kinase; Brain apoptosis associated tyrosine kinase; Brain apoptosis-associated tyrosine kinase; CDK5 binding protein; CDK5-binding protein; KIAA0641; Lemur tyrosine kinase 1; LMR1; LMTK1; LMTK1_HUMAN; p35 binding protein; p35-binding protein; p35BP; Serine/threonine protein kinase LMTK1; Serine/threonine-protein kinase LMTK1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 神经生物学 信号转导 细胞凋亡 转录调节因子 激酶和磷酸酶
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 151kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human AATK
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Function:
Apoptosis associated tyrosine kinase May be involved in neuronal differentiation.
Subunit:
Interacts with CDK5.
Subcellular Location:
Membrane; Single-pass type I membrane protein. Cytoplasm. Cytoplasm, perinuclear region.
Tissue Specificity:
Expressed in brain, and, to a lower extent, in kidney, heart, lung and skeletal muscle. Belongs to the protein kinase superfamily. Tyr protein kinase family.
Similarity:
Belongs to the protein kinase superfamily. Tyr protein kinase family.
Contains 1 protein kinase domain.
Database links:Entrez Gene: 9625 Human
Omim: 605276 Human
SwissProt: Q6ZMQ8 Human
Unigene: 514575 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.