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货号： bs-1518R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-1518R-PE-Cy7
- 英文名称
- Anti-Persephin/PE-Cy7
- 中文名称
- PE-Cy7标记的PSP抗体
- 别 名
- PSPN_HUMAN; PSP.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 发育生物学 神经生物学 生长因子和激素
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 14kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Persephin
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a secreted ligand of the GDNF (glial cell line-derived neurotrophic factor) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. This protein may play a role in cell death, and nervous system development and function. Elevated expression of this gene has been observed in oral squamous cell carcinoma. [provided by RefSeq, Aug 2016]
Function:
Exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons.
Subunit:
Homodimer; disulfide-linked.
Subcellular Location:
Secreted.
Similarity:
Belongs to the TGF-beta family. GDNF subfamily.
Database links:Entrez Gene: 5623 Human
Omim: 602921 Human
SwissProt: O60542 Human
Unigene: 248159 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经生物学相关蛋白（Neurobiology）
PSP是TGF-β家族的一个新亚族，该亚族还有其他三个成员：Neurturin(NTN)、GDNF和Artemin(ART)，它们均不同程度地对多巴胺神经元、脊髓前角运动神经元、背根神经节、颈上神经节以及肾等非神经元细胞都具有生长促进作用。研究表明胶质细胞系源性神经营养因子,主要用于PD的研究。