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货号： bs-1671R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-1671R-PE-Cy7
- 英文名称
- Anti-CCR2 + CCR5/PE-Cy7
- 中文名称
- PE-Cy7标记的细胞表面趋化因子受体2A抗体
- 别 名
- CC-CKR-2; C-C Chemokine receptor 2A; C C CKR 2; CC chemokine receptor type 2; CC CKR 2; CCCKR2; CCR 2; CCR1L; CCR2A; CCR2B; CCR5L; CD192; CD192 antigen; Chemokine C C motif receptor 2; Chemokine CC Motif Receptor 2; CKR 2; CKR2; CKR2A; CKR2B; CMKBR2; MCP 1 R; MCP1 RECEPTOR; MCP1R; Monocyte chemoattractant protein 1 receptor; Monocyte Chemotactic Protein 1 Receptor; FLJ78302; MCP-1-R; MGC103828; MGC111760; MGC168006; CCR2_MOUSE; CCR5_HUMAN; CCR2_HUMAN; C-C chemokine receptor 5; CCR5; CC-CKR-5;CCR-5; CCCKR5; CD195; CD 195; CKR-5; CKR5; CMKBR5; FLJ78003; IDDM22; AM4-7; C C chemokine receptor type 5; C-C motif chemokine receptor 5 A159A; CC Chemokine Receptor Type 5; CCR5 chemokine (C C motif) receptor 5; Chemokine receptor CCR5; CHEMR13; HIV 1 Fusion Coreceptor; HIV1 fusion coreceptor; IDDM22; MIP-1 alpha receptor; .
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞膜受体
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Horse,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 43kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from mouse CCR2 and CCR5
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009].
Function:
Receptor for the MCP-1 (JE), MCP-3 (FIC) and MCP-5 chemokines. Transduces a signal by increasing the intracellular calcium ions level.
Subunit:
Interacts with ARRB1.
Subcellular Location:
Cell membrane; Multi-pass membrane protein.
Tissue Specificity:
Detected in monocyte/macrophage cell lines, but not in nonhematopoietic cell lines.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
Database links:Entrez Gene: 12772 Mouse
Entrez Gene: 729230 Human
Entrez Gene: 60463 Rat
Omim: 601267 Human
SwissProt: P41597 Human
SwissProt: P51683 Mouse
SwissProt: O55193 Rat
Unigene: 511794 Human
Unigene: 705362 Human
Unigene: 6272 Mouse
Unigene: 211983 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.