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货号： bs-1780R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-1780R-PE-Cy7
- 英文名称
- Anti-CCRK/PE-Cy7
- 中文名称
- PE-Cy7标记的细胞周期相关激酶抗体
- 别 名
- CDK20; Cell cycle related kinase; p42; CAK kinase p42; CDCH; CDK activating kinase p42; Cell cycle related kinase; Cyclin dependent protein kinase H; Cyclin kinase activating kinase p42. CAK-kinase p42; Cyclin-dependent kinase 20; Cell cycle-related kinase; Cell division protein kinase 20.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞膜受体
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 38kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CCRK
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene contains a kinase domain most closely related to the cyclin-dependent protein kinases. The encoded kinase may activate cyclin-dependent kinase 2 and is involved in cell growth. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Dec 2009]
Function:
Required for high-level Shh responses in the developing neural tube. Together with BROMI, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity). Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue Thr-160.
Subunit:
Monomer. Interacts with BROMI.
Subcellular Location:
Nucleus. Cytoplasm. Cell projection, cilium.
Similarity:
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Contains 1 protein kinase domain.
Database links:Entrez Gene: 23552 Human
Entrez Gene: 105278 Mouse
Entrez Gene: 364666 Rat
Omim: 610076 Human
SwissProt: Q8IZL9 Human
SwissProt: Q9JHU3 Mouse
SwissProt: Q4KM34 Rat
Unigene: 522274 Human
Unigene: 74982 Mouse
Unigene: 7013 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.