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货号： bs-1683R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-1683R-PE-Cy7
- 英文名称
- Anti-CNR1/PE-Cy7
- 中文名称
- PE-Cy7标记的钙粘蛋白相关的神经受体1抗体
- 别 名
- Cannabinoid Receptor I; CANN 6; CANN6; Cannabinoid receptor I brain; CB 1; CB R; CB1; CB1A; CB1K5; CbR; Central cannabinoid receptor; Central cannabinoid receptor isoform a; Central cannabinoid receptor isoform b; CNR 1; CNR; CNR-1; CNR1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 神经生物学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 52kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CNR-1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009]
Function:
Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding.
Subunit:
Interacts (via C-terminus) with CNRIP1.
Subcellular Location:
Cell membrane.
Tissue Specificity:
Widely expressed.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
Database links:Entrez Gene: 1268 Human
Entrez Gene: 12801 Mouse
Entrez Gene: 25248 Rat
Entrez Gene: 281087 Cow
Entrez Gene: 481913 Dog
Omim: 114610 Human
SwissProt: Q5IS73 Chimpanzee
SwissProt: P21554 Human
SwissProt: P47746 Mouse
SwissProt: P20272 Rat
Unigene: 709067 Human
Unigene: 75110 Human
Unigene: 7992 Mouse
Unigene: 222240 Rat
Unigene: 89774 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CB1又称大麻素受体1,可导致大麻素类物质作用及代谢异常,从而影响胃肠动力及感觉.