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货号： bs-1697R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-1697R-PE-Cy7
- 英文名称
- Anti-DEFA1/alpha Defensin 1/PE-Cy7
- 中文名称
- PE-Cy7标记的防御素α1/3抗体
- 别 名
- Defensin, alpha 1; alpha Defensin 1/3; alpha Defensin 1+3; ; Defensin alpha 3; HNP1; HNP3; HP1; DEF1_HUMAN; Neutrophil defensin 1; HNP-1; HP-1; HP1; HP 1-56; Neutrophil defensin 1; Neutrophil defensin 2; HNP-2; HP-2; HP2; DEFA1; DEF1; DEFA2; MRS; DEF3_HUMAN; Neutrophil defensin 3; Defensin, alpha 3; HNP-3; HP-3; HP3; HP 3-56;
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 6.7kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human alpha Defensin 1/3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Defensins are a group of cyclic peptides containing 29-35 amino acids, which comprise approximately 30% of the total protein content of neutrophil azurophilic granules. Various functions have been reported for the defensins, including antibacterial and antifungal activity and chemotactic activity for monocytes.
Function:
Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.
Subunit:
Dimer.
Subcellular Location:
Secreted.
Post-translational modifications:
ADP-ribosylation drastically reduces cytotoxic and antibacterial activities, and enhances IL8 production.
Phosphorylation at Tyr-85 has been found in some cancer cell lines, and interferes with ADP-rybosylation.
Similarity:
Belongs to the alpha-defensin family.
Database links:Entrez Gene: 1667 Human
Entrez Gene: 1668 Human
Entrez Gene: 728358 Human
Entrez Gene: 13216 Mouse
Omim: 125220 Human
SwissProt: P59665 Human
SwissProt: P59666 Human
SwissProt: P11477 Mouse
Unigene: 380781 Human
Unigene: 654448 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.