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货号： bs-1910R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-1910R-PE-Cy7
- 英文名称
- Anti-TGF beta Receptor III/PE-Cy7
- 中文名称
- PE-Cy7标记的转移生长因子β受体3抗体
- 别 名
- Beta glycan; TGF Beta R3; Betaglycan; Betaglycan proteoglycan; BGCAN; TGF beta receptor type 3; TGF-beta receptor type 3; TGF beta receptor type III; TGF-beta receptor type III; TGFB R3; TGFBR 3; TGFBR3; TGFR 3; TGFR-3; TGFR3; Transforming Growth Factor Beta Receptor III; Transforming growth factor beta receptor III betaglycan 300kDa; TGF-βRⅢ; TGFβRⅢ; TGFβ RIII; TGF β RIII; TGF-β RIII; TGFβ-RIII; Transforming growth factor beta receptor type 3.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 神经生物学 信号转导 干细胞 细胞凋亡 生长因子和激素 激酶和磷酸酶
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Sheep,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 94kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human TGFBR3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010].
Function:
Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.
Subunit:
Interacts with TCTEX1D4.
Subcellular Location:
Secreted. Secreted > extracellular space. Cell membrane. Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.
Post-translational modifications:
Extensively modified by glycosaminoglycan groups (GAG).
Similarity:
Contains 1 ZP domain.
Database links:Entrez Gene: 7049 Human
Entrez Gene: 21814 Mouse
Omim: 600742 Human
SwissProt: Q03167 Human
SwissProt: O88393 Mouse
Unigene: 482390 Human
Unigene: 200775 Mous
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
转化生长因子β受体Ⅲ，TGFβRⅢ