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货号： bs-1941R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-1941R-PE-Cy7
- 英文名称
- Anti-Zfp91/PE-Cy7
- 中文名称
- PE-Cy7标记的白血病相关新基因抗体
- 别 名
- zinc finger protein 91; FKSG11; HGNC:14983; PZF; zinc finger protein 91 homolog (mouse); zinc finger protein homologous to mouse Zfp91; ZFP91_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 染色质和核信号 神经生物学 细胞凋亡 转录调节因子 结合蛋白 细胞分化
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 63kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Zfp91
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by ZFP91 is a member of the zinc finger family of proteins. This protein contains C2H2 type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. May be involved in transcriptional regulation. May play an important role in cell proliferation and/or anti-apoptosis Found in all the examined tissues including brain, heart, kidney, lung, liver, spleen, thymus, skeletal muscle, ovary and testis. Belongs to the krueppel C2H2-type zinc-finger protein family.
Function:
Atypical E3 ubiquitin-protein ligase that mediates Lys-63-linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby acts as an activator of the non-canonical NF-kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis.
Subunit:
Interacts with MAP3K14/NIK.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed ubiquitously, particularly at high level in testis. Isoform 2 is testis specific.
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 5 C2H2-type zinc fingers.
Database links:Entrez Gene: 80829 Human
Entrez Gene: 109910 Mouse
Entrez Gene: 246282 Rat
SwissProt: Q96JP5 Human
SwissProt: Q62511 Mouse
Unigene: 524920 Human
Unigene: 290924 Mouse
Unigene: 1772 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.