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货号： bs-1959R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-1959R-PE-Cy7
- 英文名称
- Anti-IL2 Receptor beta/PE-Cy7
- 中文名称
- PE-Cy7标记的白介素2受体β链/IL-2Rβ 抗体
- 别 名
- Imterleukm-2 Receptor beta; CD 122; CD122; CD122 antigen; High affinity IL 2 receptor beta subunit; High affinity IL 2 receptor subunit beta; High affinity IL2 receptor beta subunit; High affinity IL2 receptor subunit beta; High affinity IL-2 receptor subunit beta; IL 2 receptor; IL-2 receptor; IL-2 receptor subunit beta; IL-2R subunit beta; IL-2RB; IL15RB; IL2 R B; IL-2 R B; IL2 RB; IL2 receptor; IL2RB; Interleukin 2 receptor beta; Interleukin 2 receptor subunit beta; Interleukin-2 receptor subunit beta; OTTHUMP00000028799; P70 75; P7075; p75; IL2RB_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 免疫学 细胞粘附分子 细胞表面分子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow, Horse,
- 产品应用
- Flow-Cyt=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 58kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CD122
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq, Jul 2008].
Function:
Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
Subunit:
Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. Interacts with SHB upon interleukin stimulation. Interacts with HTLV-1 accessory protein p12I.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Similarity:
Belongs to the type I cytokine receptor family. Type 4 subfamily.
Contains 1 fibronectin type-III domain.
Database links:Entrez Gene: 3560 Human
Entrez Gene: 16185 Mouse
Omim: 146710 Human
SwissProt: P14784 Human
SwissProt: P16297 Mouse
Unigene: 474787 Human
Unigene: 35287 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.