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货号： bs-2416R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-2416R-PE-Cy7
- 英文名称
- Anti-NKG2C/PE-Cy7
- 中文名称
- PE-Cy7标记的NK细胞受体2C抗体
- 别 名
- Natural killer cell group 2C; natural killer cell protein group 2-C; NKG2-C type II integral membrane protein; NKG2-C-activating NK receptor; NK cell receptor C; CD159 antigen-like family member C; CD159c; KLRC2 protein; NKG2C_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- Flow-Cyt=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 26kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NKG2C
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Natural killer (NK) cells are lymphocytes that can mediate the lysis of certain tumor cells and virus infected cells without being previously activated. They can also regulate specific humoral and cell mediated immunity. NK cells preferentially express several calcium dependent (C type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C type lectin genes preferentially expressed on NK cells.
Function:
Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
Subunit:
Can form disulfide-bonded heterodimer with CD94. Interacts with TYROBP.
Subcellular Location:
Membrane; Single-pass type II membrane protein.
Tissue Specificity:
Natural killer cells.
Similarity:
Contains 1 C-type lectin domain.
Database links:Entrez Gene: 3822 Human
Omim: 602891 Human
SwissProt: Q9GME8 Chimpanzee
SwissProt: P26717 Human
SwissProt: Q9MZK6 Rhesus monkey
Unigene: 591157 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
自然杀伤细胞活化性受体2C