产品中心
当前位置：首页>产品中心Anti-RAE1/PE-Cy7
货号： bs-3791R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-3791R-PE-Cy7
- 英文名称
- Anti-RAE1/PE-Cy7
- 中文名称
- PE-Cy7标记的mRNA结合蛋白抗体
- 别 名
- RAE-1; MIG 14; MIG14; Mnrp 41; Mnrp41; mRNA associated protein mrnp 41; mRNA binding protein 41 kD; mRNA export protein; MRNP 41; MRNP41; RAE 1; RAE1 (RNA export 1 S.pombe) homolog; RAE1 homolog; Rae1 protein homolog; RAE1 RNA export 1 homolog; RNA export 1; RNA export 1 homolog; Homolog of yeast Rae1 mRNA associated protein of 41 kDa. RAE1L_HUMAN
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 信号转导 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 41kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human RAE1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Mutations in Rae1 and Gle2(Saccharomyces cerevisae homolog) genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Depletion of Rae1 from extracts or cells severely inhibits mitotic spindle assembly. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Function:
Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton.
Subunit:
Interacts with NUP98.
Subcellular Location:
Cytoplasm. Nucleus.
Similarity:
Belongs to the WD repeat rae1 family.
Contains 7 WD repeats.
Database links:Entrez Gene: 8480 Human
Omim: 603343 Human
SwissProt: P78406 Human
SwissProt: Q3SYL7 Human
Unigene: 371698 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.