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货号： bs-2523R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-2523R-PE-Cy7
- 英文名称
- Anti-CD99/PE-Cy7
- 中文名称
- PE-Cy7标记的CD99抗体
- 别 名
- T-cell surface glycoprotein E; T cell surface glycoprotein E2 precursor; 12E7; Antigen identified by monoclonal 12E7 Y homolog; Antigen identified by monoclonal antibodies 12E7 F21 and O13; CD 99; CD99 antigen; CD99 molecule; CD99X; E2 antigen; Ewing Sarcoma; MIC 2; MIC 2X; MIC 2Y; MIC2; MIC2X; MIC2Y; Monoclonal antibody 12E7; MSK5X; Protein MIC2; Surface antigen MIC2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 细胞表面分子 糖蛋白 细胞类型标志物 t-淋巴细胞
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Mouse, Rat,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 16kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from mouse CD99
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. Cyclophilin A binds to CD99 and may act as a signaling regulator of CD99. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Function:
Involved in T-cell adhesion processes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1.
Subunit:
Homodimer. Interacts with PILRB.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Natural killer cells.
Similarity:
Belongs to the CD99 family.
Database links:Entrez Gene: 4267 Human
Entrez Gene: 673094 Mouse
Omim: 313470 Human
SwissProt: P14209 Human
SwissProt: Q8VCN6 Mouse
Unigene: 653349 Human
Unigene: 423040 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CD99（P30/32MIC2）是一种跨膜蛋白，为MIC2基因产物。分布于淋巴细胞、胸腺皮质细胞、卵巢的颗粒细胞、胰岛细胞和睾丸支持细胞。