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货号： bs-2569R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-2569R-PE-Cy7
- 英文名称
- Anti-CD226/PE-Cy7
- 中文名称
- PE-Cy7标记的CD226抗体
- 别 名
- DNAX accessory molecule 1; adhesion glycoprotein; CD226 antigen; DNAM1; platelet and T cell activation antigen 1; PTA1; TLiSA1; CD226; CD226 molecule; CD226_HUMAN; DNAM 1; DNAM-1; T lineage specific activation antigen 1 antigen.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 免疫学 细胞粘附分子 细胞表面分子 细胞类型标志物 自然杀伤细胞 淋巴细胞 t-淋巴细胞 b-淋巴细胞
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,
- 产品应用
- Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 35kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CD226
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. [provided by RefSeq, Jul 2008]
Subunit:
Interacts with PVR and PVRL2.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Expressed by peripheral blood T-lymphocytes.
Similarity:
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Database links:Entrez Gene: 10666 Human
Omim: 605397 Human
SwissProt: Q15762 Human
Unigene: 660130 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CD226分子是一种广泛表达于多种免疫细胞膜表面的Ⅰ型跨膜糖蛋白，CD226广泛表达于T细胞、NK细胞、NK T细胞、活化的血管内皮细胞、巨核/血小板谱系、单核细胞、胸腺细胞、某些B细胞亚群、部分造血干细胞和肥大细胞等免疫细胞表面，在免疫系统以外则分布于海马和小脑皮质的神经突触部位。CD226与其配体的相互作用参与CTL和NK细胞的活化、分化和细胞毒作用,调节CD4+ T细胞的增殖和分化，介导内皮细胞与其他细胞的黏附,促进血小板的活化与聚集，参与造血调控，介导肥大细胞的脱颗粒作用，参与NK T细胞和胸腺细胞的抗凋亡作用、树突状细胞的成熟、免疫突触和神经突触的形成，并与肿瘤、自身免疫性疾病、移植排斥及病毒感染等疾病密切相关。