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货号： bs-2682R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-2682R-PE-Cy7
- 英文名称
- Anti-SLAMF6/LY108/PE-Cy7
- 中文名称
- PE-Cy7标记的SLAMF6抗体
- 别 名
- LY108; Activating NK receptor; KALI; KALIb; MGC104953; NK T B antigen; NTB A; NTBA; SF2000; SLAM family member 6; SLAM family member 6 precursor; SLAMF6; SLAF6_HUMAN; NK-T-B-antigen; NTB-A; CD352.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 免疫学 细胞表面分子 细胞类型标志物 自然杀伤细胞
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Mouse, Rat,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 37kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from mouse SLAMF6
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
SLAMF6 is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. It may play a role in the regulation of autoimmune diseases.
Function:
Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors.
Subunit:
Homodimer. Interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP.
Subcellular Location:
Cell membrane; Single-pass type I membrane protein (Probable).
Tissue Specificity:
Expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes.
Similarity:
Contains 1 Ig-like (immunoglobulin-like) domain.
Database links:Entrez Gene: 114836 Human
Entrez Gene: 30925 Mouse
Omim: 606446 Human
SwissProt: Q96DU3 Human
SwissProt: Q9ET39 Mouse
Unigene: 492348 Human
Unigene: 486404 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.