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货号： bs-2730R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-2730R-PE-Cy7
- 英文名称
- Anti-ULBP3/PE-Cy7
- 中文名称
- PE-Cy7标记的UL16结合蛋白3抗体
- 别 名
- ALCAN-gamma; N2DL-3; N2DL3; NKG2D ligand 3; NKG2D ligand 3 precursor; NKG2DL3; OTTHUMP00000017411; RAET1N; Retinoic acid early transcript 1N; UL16 binding protein 3; UL16-binding protein 3; N2DL3_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 免疫学 自然杀伤细胞
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 25kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ULBP3 C-terminus
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
ULBP3 is a human ligand for the NKG2D receptor, together with at least ULBP1 and ULBP2. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. ULBP3 has a lower affinity for NKG2D compared to ULBP1 and ULBP2 and induces weaker signaling responses than does ULBP2 or ULBP1.
Function:
Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP2. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. Has lower affinity for NKG2D compared to ULBP1 and ULBP2 and induces weaker signaling responses than does ULBP2 or ULBP1.
Subunit:
Does not interact with the CMV glycoprotein UL16. Does not bind to beta2-microglobulin.
Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor.
Similarity:
Belongs to the MHC class I family.
Database links:Entrez Gene: 79465 Human
Omim: 605699 Human
SwissProt: Q9BZM4 Human
Unigene: 326556 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.