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货号： bs-2761R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-2761R-PE-Cy7
- 英文名称
- Anti-DBC1/PE-Cy7
- 中文名称
- PE-Cy7标记的膀胱癌缺失基因1
- 别 名
- Deleted in bladder cancer protein 1; deleted in bladder cancer protein 1 precursor; IB3089A; DBC1; DBCCR1; FAM5A; deleted in bladder cancer protein 1 homolog precursor; BMP/retinoic acid-inducible neural-specific protein 1; BRINP; Brinp1; LOC140610; DBC 1; DBC.1; DBCCR1; Deleted in bladder cancer chromosome region candidate 1; Deleted in breast cancer 1; Deleted in breast cancer gene 1 protein; FAM5A; KIAA1967; OTTHUMP00000022751; p30 DBC; p30 DBC protein; Protein FAM5A; DBC1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 86kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human DBC1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers. It contains a 5 CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers. [provided by RefSeq].
Function:
Inhibits cell proliferation by negative regulation of the G1/S transition. Mediates cell death which is not of the classical apoptotic type and regulates expression of components of the plasminogen pathway.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Highly expressed in brain. Weakly expressed in heart, lung, skeletal muscle, kidney, thymus, prostate, testis and small intestine.
Similarity:
Belongs to the FAM5 family.
Contains 1 MACPF domain.
Database links:Entrez Gene: 1620Human
Entrez Gene: 56710Mouse
Entrez Gene: 140610Rat
Omim: 602865Human
SwissProt: O60477Human
SwissProt: Q920P3Mouse
SwissProt: Q925T8Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.