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货号： bs-3502R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-3502R-PE-Cy7
- 英文名称
- Anti-Synapsin II/PE-Cy7
- 中文名称
- PE-Cy7标记的神经突触素2抗体
- 别 名
- SYN 2; SYN II; SYN IIa; SYN IIb; SYN2; Synapsin 2; Synapsin II isoform IIa; Synapsin II isoform IIb; Synapsin2; SynapsinII; SYNII; SYNIIa; SYNIIb; SYN2_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 神经生物学 信号转导 转录调节因子 细胞表面分子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 63kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Synapsin II
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. The TIMP4 gene is located within an intron of this gene and is transcribed in the opposite direction. Mutations in this gene may be associated with abnormal presynaptic function and schizophrenia. Alternative splicing of this gene results in two transcripts. [provided by RefSeq, Jul 2008]
Function:
Neuronal phosphoprotein that coats synaptic vesicles,binds to the cytoskeleton, and is believed to function in theregulation of neurotransmitter release.
Subunit:
Interacts with CAPON.
Subcellular Location:
Cell junction, synapse.
Tissue Specificity:
Central and peripheral nervous systems.
Post-translational modifications:
Phosphorylation at Ser-10 dissociates synapsins from synapticvesicles.
Similarity:
Belongs to the synapsin family.
Database links:Entrez Gene: 6854 Human
Entrez Gene: 20965 Mouse
Entrez Gene: 29179 Rat
Omim: 600755 Human
SwissProt: Q92777 Human
SwissProt: Q64332 Mouse
SwissProt: Q63537 Rat
Unigene: 445503 Human
Unigene: 506 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.