产品中心
当前位置：首页>产品中心Anti-NFKBIL1/PE-Cy5.5
货号： bs-19224R-PE-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19224R-PE-Cy5.5
- 英文名称
- Anti-NFKBIL1/PE-Cy5.5
- 中文名称
- PE-Cy5.5标记的核因子κB抑制蛋白样蛋白1抗体
- 别 名
- I-kappa-B-like protein;IkappaBL;IKBL;IKBL1_HUMAN;Inhibitor of kappa B-like protein;LST1;NF-kappa-B inhibitor-like protein 1;NFKBIL;Nfkbil1;Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 信号转导 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 43kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NFKBIL1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a divergent member of the I-kappa-B family of proteins. Its function has not been determined. The gene lies within the major histocompatibility complex (MHC) class I region on chromosome 6. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009]
Function:
May be a negative regulator of NF-kappa-B activation.
Tissue Specificity:
Detected in different cell types including monocytes, T-cells, B-cells and hepatocytes.
DISEASE:
Defects in NFKBIL1 are a cause of susceptibility to rheumatoid arthritis (RA) [MIM:180300]. It is a systemic inflammatory disease with autoimmune features and a complex genetic component. It primarily affects the joints and is characterized by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures.
Similarity:
Contains 2 ANK repeats.
Database links:Entrez Gene: 4795Human
Entrez Gene: 18038Mouse
Entrez Gene: 361794Rat
Omim: 601022Human
SwissProt: Q9UBC1Human
SwissProt: O88995Mouse
SwissProt: Q8R2H1Rat
Unigene: 2764Human
Unigene: 300795Mouse
Unigene: 38632Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.