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货号： bs-18909R-PE-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18909R-PE-Cy5.5
- 英文名称
- Anti-MGAT4C/PE-Cy5.5
- 中文名称
- PE-Cy5.5标记的MGAT4C蛋白抗体
- 别 名
- 3-D-mannoside beta-1; 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C; 4-N-acetylglucosaminyltransferase IVc; Alpha-1; GlcNAc-T IVc; GnT-IVc; hGnT-IV-H; MGAT4C; MGT4C_HUMAN; N-acetylglucosaminyltransferase IV homolog; N-acetylglucosaminyltransferase IVc; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc; UDP-N-acetylglucosamine: alpha-1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 56kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MGAT4C
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
MGAT4C is a 478 amino acid single-pass type II membrane protein that localizes to the golgi apparatus and belongs to the glycosyltransferase 54 family. Expressed in liver, heart, testis, brain and adrenal gland, GnT-IVH functions as a glycosyltransferase that catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans, thereby playing a crucial role in the production of tri- and tetra-antennary N-linked sugar chains. The gene encoding GnT-IVH maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
Function:
Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains (By similarity). Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage (GnT-VI activity).
Subcellular Location:
Golgi apparatus membrane.
Tissue Specificity:
Expressed in heart, adrenal gland, testis, liver, brain and fetal brain. Not expressed in pancreas.
Similarity:
Belongs to the glycosyltransferase 54 family.
Database links:Entrez Gene: 25834Human
SwissProt: Q9UBM8Human
Unigene: 589093Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.