产品中心
当前位置：首页>产品中心Anti-LIN54/PE-Cy5.5
货号： bs-18280R-PE-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18280R-PE-Cy5.5
- 英文名称
- Anti-LIN54/PE-Cy5.5
- 中文名称
- PE-Cy5.5标记的LIN54蛋白抗体
- 别 名
- CXC domain-containing protein 1; CXCDC1; DKFZp686L1814; JC8.6; KIAA2037; Lin54; LIN54_HUMAN; MGC129905; MIP120; Protein lin-54 homolog.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 80kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human LIN54
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
LIN54 is a component of the LIN, or DREAM, complex, an essential regulator of cell cycle genes (Schmit et al., 2009 [PubMed 19725879]).[supplied by OMIM, Dec 2010]
Function:
Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. In G0 phase, the complex binds to more than 800 promoters and is required for repression of E2F target genes. In S phase, the complex selectively binds to the promoters of G2/M genes whose products are required for mitosis and participates in their cell cycle dependent activation. In the complex, acts as a DNA-binding protein that binds the promoter of CDK1 in a sequence-specific manner.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the lin-54 family.
Contains 2 CXC domains.
Database links:Entrez Gene: 132660Human
Entrez Gene: 231506Mouse
Entrez Gene: 305171Rat
SwissProt: Q6MZP7Human
SwissProt: Q571G4Mouse
SwissProt: Q641Z1Rat
Unigene: 96952Human
Unigene: 212568Mouse
Unigene: 24111Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.