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货号： bs-18226R-PE-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18226R-PE-Cy5.5
- 英文名称
- Anti-PENK(237-258)/PE-Cy5.5
- 中文名称
- PE-Cy5.5标记的脑啡肽A抗体
- 别 名
- EP-ENK; Enkephalin A; P ENK; Preproencephalin A; Proenkephalin A; Proenkephalin; Synenkephalin; Proenkephalin; Opioid growth factor; OGF; PENK protein; ProenkephalinA; PENK_HUMAN; Met-enkephalin-Arg-Gly-Leu; Met-enkephalin-Arg-Phe; Synenkephalin; PENK(114-133); PENK(143-183); PENK(237-258).
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Horse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 28kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PENK
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the pentapeptide opioids Met-enkephalin and Leu-enkephalin, which are stored in synaptic vesicles, then released into the synapse where they bind to mu- and delta-opioid receptors to modulate the perception of pain. Other non-opioid cleavage products may function in distinct biological activities. [provided by RefSeq, Jul 2015]
Function:
Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK(114-133) and PENK(237-258) increase glutamate release in the striatum. PENK(114-133) decreases GABA concentration in the striatum.
Subcellular Location:
Secreted.
Post-translational modifications:
The N-terminal domain contains 6 conserved cysteines thought to be involved in disulfide bonding and/or processing.
Similarity:
Belongs to the opioid neuropeptide precursor family.
Database links:Entrez Gene: 5179 Human
Entrez Gene: 18619 Mouse
Entrez Gene: 29237 Rat
Omim: 131330 Human
SwissProt: P01210 Human
SwissProt: P22005 Mouse
SwissProt: P04094 Rat
Unigene: 339831 Human
Unigene: 475097 Mouse
Unigene: 10015 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.