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货号： bs-17328R-PE-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17328R-PE-Cy5.5
- 英文名称
- Anti-TOX3/PE-Cy5.5
- 中文名称
- PE-Cy5.5标记的TOX3蛋白抗体
- 别 名
- BC052044; C230068E13; CAG trinucleotide repeat-containing gene F9 protein; CAGF9; TNRC9; TOX high mobility group box family member 3; TOX3; TOX3_HUMAN; Trinucleotide repeat containing 9; Trinucleotide repeat containing gene 9 protein.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 结合蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Horse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 63kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human TOX3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- Function:
Transcriptional coactivator of the p300/CBP-mediated trancription complex. Activates transactivation through cAMP response element (CRE) sites. Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts. Stimulates transcription from the estrogen-responsive or BCL-2 promoters. Required for depolarization-induced transcription activation of the C-FOS promoter in neurons. Associates with chromatin to the estrogen-responsive C3 promoter region.
Subunit:
Homodimer. Interacts with CREB1; the interaction is not depolarization dependent. Interacts with CREBBP (via C-terminus) (By similarity). Interacts (via HGM box) with CITED1 (via C-terminus); the interaction increases estrogen-response element (ERE)-dependent transcription and protection against cell death. Interacts with CREB1 (phosphorylated form).
Subcellular Location:
Nucleus (Probable).
Tissue Specificity:
Expressed mainly in epithelial cells. Expressed in the central nervous system (CNS), in the ileum and within the brain in the frontal and occipital lobe.
Similarity:
Contains 1 HMG box DNA-binding domain.
Database links:Entrez Gene: 27324Human
Entrez Gene: 244579Mouse
Entrez Gene: 291908Rat
Omim: 611416Human
SwissProt: O15405Human
SwissProt: Q80W03Mouse
SwissProt: B7SBD2Rat
Unigene: 460789Human
Unigene: 302755Mouse
Unigene: 41060Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.