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货号： bs-17326R-PE-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17326R-PE-Cy5.5
- 英文名称
- Anti-LULL1/TOR1AIP2/PE-Cy5.5
- 中文名称
- PE-Cy5.5标记的LULL1蛋白抗体
- 别 名
- TOR1AIP2;IFRG15; Interferon responsive gene 15; LULL1; Lumenal domain like LAP1; NET9; RP11-12M5.5; TOR1AIP2; Torsin 1A interacting protein 2; Torsin A interacting protein 2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 51kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human LULL1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
LULL1 is a 470 amino acid endoplasmic reticulum single-pass membrane protein belonging to the TOR1AIP family. LULL1 interacts with torsinA, an essential AAA+ ATPase found in the endoplasmic reticulum (ER) and nuclear envelope (NE) of higher eukaryotes. LULL1 regulates the distribution and activity of torsinA within the ER and NE lumen and reveals functional defects in mutant torsinA, which is responsible for DYT1 dystonia, a neurodevelopmental disease caused by an in-frame deletion (Deltagag) in the gene encoding torsinA. The gene encoding LULL1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
Function:
Regulates the distribution of TOR1A between the endoplasmic reticulum and the nuclear envelope.
Subunit:
Interacts with TOR1A and TOR1B (ATP-bound).
Subcellular Location:
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane.
Database links:Entrez Gene: 163590Human
Entrez Gene: 304881Rat
Omim: 614513Human
SwissProt: Q8NFQ8Human
SwissProt: Q6P752Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.