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货号： bs-17260R-PE-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17260R-PE-Cy5.5
- 英文名称
- Anti-SCAI/PE-Cy5.5
- 中文名称
- PE-Cy5.5标记的肿瘤细胞转移抑制蛋白抗体
- 别 名
- C9orf126; FLJ11758; FLJ36664; MGC120525; MGC120526; MGC120528; NET40; Protein SCAI; SCAI; SCAI_HUMAN; Suppressor of cancer cell invasion; Suppressor of cancer cell invasion protein.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 信号转导 细胞类型标志物 G蛋白信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 70kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SCAI
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a regulator of cell migration. The encoded protein appears to function in the RhoA (ras homolog gene family, member A)-Dia1 (diaphanous homolog 1) signal transduction pathway. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]
Function:
Tumor suppressor which functions to suppress MKL1-induced SRF transcriptional activity. May function in the RHOA-DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of ITGB1.
Subunit:
Interacts with DIAPH1 (By similarity). Forms a nuclear ternary complex with MKL1 and SRF.
Subcellular Location:
Membrane. Nucleus. Cytoplasm. Nuclear localization is required for inhibition of MKL1.
Similarity:
Belongs to the SCAI family.
Database links:Entrez Gene: 286205Human
Entrez Gene: 320271Mouse
Entrez Gene: 690538Rat
SwissProt: Q8N9R8Human
SwissProt: Q8C8N2Mouse
Unigene: 59504Human
Unigene: 204836Mouse
Unigene: 206053Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.