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货号： bs-17210R-PE-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17210R-PE-Cy5.5
- 英文名称
- Anti-JRK/PE-Cy5.5
- 中文名称
- PE-Cy5.5标记的JRK蛋白抗体
- 别 名
- Jerky; Jerky (mouse) homolog; Jerky homolog (mouse); JH8.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 转录调节因子 结合蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow, Horse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 57kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human JRK
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a conserved protein that is similar to DNA-binding proteins, such as major centromere autoantigen B (CENPB). Inactivation of the related gene in mice resulted in epileptic seizures. Childhood Absence Epilepsy (CAE) has been mapped to the same chromosomal location (8q24.3) as this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Function:
The JRK gene is the human homolog of the mouse jerky gene. The encoded protein has similarity to several nuclear regulatory proteins, including centromere protein B, which indicates that it might function as a DNA binding protein. Insertional inactivation of this gene in transgenic mice results in epileptic seizures. JRK is a strong candidate for Childhood Absence Epilepsy (CAE) as it has been mapped to the same chromosomal location (8q24.3). Two transcript variants encoding different isoforms have been found for this gene.
Subcellular Location:
Nuclear
Database links:Entrez Gene: 8629Human
Omim: 603210Human
SwissProt: O75564Human
Unigene: 535903Human
Unigene: 683465Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.