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货号： bs-16408R-PE-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-16408R-PE-Cy5.5
- 英文名称
- Anti-ZRSR2/PE-Cy5.5
- 中文名称
- PE-Cy5.5标记的ZRSR2蛋白抗体
- 别 名
- CCCH type zinc finger, RNA binding motif and serine/arginine rich protein 2; MGC142014; U2AFM_HUMAN; MGC142040; Renal carcinoma antigen NY REN 20; U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit related protein 2; U2(RNU2) small nuclear RNA auxiliary factor 1 like 2; U2AF1 RS2; U2AF1L2; U2AF1RS2; U2AF35-related protein; URP; Zinc finger-, CCCH domain-, and RNA-binding motif-containing serine/arginine-rich protein 2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 58kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ZRSR2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes an essential splicing factor. The encoded protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3 splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly. [provided by RefSeq, Jul 2008]
Function:
ZRSR2 is an essential splicing factor. The protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3 splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly. This gene encodes U2AF small subunit related protein 2 which is an essential splicing factor. This protein is associated with the U2AF heterodimer composed of a large and a small subunit. It specifically interacts with the large subunit through an U2AF small subunit homologous region, and with SR proteins through its RS domain. This protein and U2AF small subunit are not functionally redundant.
Subunit:
Component of the U11/U12 snRNPs that are part of the U12-type spliceosome. Interacts (via RS domain) with SRSF1 and SRSF2. Interacts with U2AF2/U2AF65.
Subcellular Location:
Nuclear
Tissue Specificity:
Widely expressed.
Post-translational modifications:
Phosphorylated in the RS domain by SRPK1.
Similarity:
Contains 2 C3H1-type zinc fingers.
Contains 1 RRM (RNA recognition motif) domain.
Database links:Entrez Gene: 8233Human
Entrez Gene: 22184Mouse
Entrez Gene: 302670Rat
Omim: 300028Human
SwissProt: Q15696Human
SwissProt: Q62377Mouse
Unigene: 171909Human
Unigene: 426178Mouse
Unigene: 26786Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.