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货号： bs-16176R-PE-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-16176R-PE-Cy5.5
- 英文名称
- Anti-FOXR2/PE-Cy5.5
- 中文名称
- PE-Cy5.5标记的叉头蛋白R2抗体
- 别 名
- Forkhead box protein N6; Forkhead box protein R2; FOXN6; FOXR2_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 36kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human FOXR2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that express proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXR2 (Forkhead box protein R2), also known as FOXN6 (Forkhead box protein N6), is a 311 amino acid nuclear protein that belongs to the FOX family and contains one fork-head DNA-binding domain. Like other members of the FOX family, FOXR2 is not abundantly expressed in normal tissues but is found at very high levels in breast cancer and primary cancer cell lines and is thought to act as a transcription factor. Through chromosomal aberrations such as retroviral integration, gene amplification or translocation, FOXR2 may be involved the development of certain invasive carcinomas.
Function:
Forkhead-box (FOX) transcription factors are implicated in carcinogenesis through gene amplification, retroviral integration, or chromosomal translocation. Human FOXR2 mRNA was expressed in breast cancer cell line and primary breast cancer.
Subcellular Location:
Nuclear
Tissue Specificity:
Expressed in breast cancer cell lines and primary cancer.
Similarity:
Contains 1 fork-head DNA-binding domain.
Database links:Entrez Gene: 139628Human
SwissProt: Q6PJQ5Human
Unigene: 364260Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.