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货号： bs-4498R-PE-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4498R-PE-Cy5.5
- 英文名称
- Anti-PER-3/PE-Cy5.5
- 中文名称
- PE-Cy5.5标记的生物钟蛋白3抗体
- 别 名
- 2810049O06Rik; Cell growth inhibiting gene 13 protein; Cell growth-inhibiting gene 13 protein; Circadian clock protein PERIOD 3; GIG13; gPER3; HGNC:8847; hPER3; mPer3; Per3; PER3_HUMAN; Period circadian protein homolog 3; Period homolog 3 (Drosophila); Period homolog 3; Period homolog 3, Drosophila; Period3.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 心血管 细胞生物 细胞周期蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 132kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PER-3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Circadian expression in the suprachiasmatic nucleus continues in constant darkness, and a shift in the light/dark cycle evokes a proportional shift of gene expression in the suprachiasmatic nucleus. The specific function of this gene is not yet known. [provided by RefSeq, Jul 2008]
Function:
Component of the circadian clock mechanism which is essential for generating circadian rhythms. Can bind heme.
Subcellular Location:
Cytoplasm. Nucleus. Mainly cytoplasmic. Translocates to the nucleus through binding PER1, PER2, CRY1 or CRY2, but not TIMELESS.
Post-translational modifications:
Phosphorylation appears to require association with PER1 and translocation to the nucleus.
Ubiquitinated.
Similarity:
Contains 1 PAC (PAS-associated C-terminal) domain.
Contains 2 PAS (PER-ARNT-SIM) domains.
Database links:Entrez Gene: 8863Human
Entrez Gene: 18628Mouse
Entrez Gene: 78962Rat
Omim: 603427Human
SwissProt: P56645Human
SwissProt: O70361Mouse
SwissProt: Q8CJE2Rat
Unigene: 162200Human
Unigene: 121361Mouse
Unigene: 230006Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.