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货号： bs-10292R-PE-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-10292R-PE-Cy5.5
- 英文名称
- Anti-TBCEL/PE-Cy5.5
- 中文名称
- PE-Cy5.5标记的微管蛋白折叠辅助因子E样抗体
- 别 名
- EL; Leucine-rich repeat-containing protein 35; LRRC35; TBCEL; TBCEL_HUMAN; Tubulin folding cofactor E-like; Tubulin-specific chaperone cofactor E-like protein.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 48kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human TBCEL
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
TBCEL is a 424 amino acid cytoplasmic protein that acts as a regulator of tubulin stability. While abundantly expressed in testis, TBCEL is also present in several tissues at a much lower level. TBCEL contains seven LRR (leucine-rich) repeats, one LRRCT domain and one ubiquitin-like domain. The gene that encodes TBCEL consists of 66,704 bases and maps to human chromosome 11q23.3. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that map to chromosome 11.
Function:
Acts as a regulator of tubulin stability.
Subcellular Location:
Cytoplasm >cytoskeleton.
Tissue Specificity:
Abundantly expressed in testis, but is also present in several tissues at a much lower level.
Similarity:
Contains 7 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 ubiquitin-like domain.
Database links:Entrez Gene: 219899Human
Omim: 610451Human
SwissProt: Q5QJ74Human
Unigene: 504136Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.