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货号： bs-14304R-PE-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-14304R-PE-Cy5.5
- 英文名称
- Anti-DBR1/PE-Cy5.5
- 中文名称
- PE-Cy5.5标记的脱支酶同源蛋白DBR1抗体
- 别 名
- DBR1; DBR1_HUMAN; Debranching enzyme homolog 1 (S. cerevisiae); Lariat debranching enzyme; RNA lariat debranching enzyme.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 62kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human DBR1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene is an RNA lariat debranching enzyme that hydrolyzes 2-5 prime branched phosphodiester bonds. The encoded protein specifically targets the bonds at the branch point of excised lariat intron RNA, converting them to linear molecules that are then degraded. This protein may also be involved in retroviral replication. [provided by RefSeq, Nov 2011]
Function:
Cleaves the 2-5 phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via a RNA lariat intermediate in cDNA synthesis.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the lariat debranching enzyme family.
Database links:Entrez Gene: 51163Human
Entrez Gene: 83703Mouse
Entrez Gene: 681234Rat
Omim: 607024Human
SwissProt: Q9UK59Human
SwissProt: Q923B1Mouse
Unigene: 477700Human
Unigene: 31324Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.