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货号： bs-14198R-PE-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-14198R-PE-Cy5.5
- 英文名称
- Anti-DARS2/PE-Cy5.5
- 中文名称
- PE-Cy5.5标记的天门冬氨酰tRNA连接酶2抗体
- 别 名
- Aspartate tRNA ligase 2 mitochondrial; Aspartate tRNA ligase; Aspartate tRNA ligase mitochondrial; Aspartyl tRNA synthetase 2 (mitochondrial); Aspartyl tRNA synthetase mitochondrial; AspRS; FLJ10514; SYDM_HUMAN; LBSL; MT ASPRS; RP3 383J4.2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 新陈代谢 线粒体 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 68kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human DARS2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL). [provided by RefSeq, Nov 2009]
Function:
Aspartyl-tRNA synthetase (DARS) charges its cognate tRNA with aspartate during protein biosynthesis. Mammalian synthetases differ from those of prokaryotes and lower eukaryotes in that they associate as multienzyme complexes. Defects in DARS2 are a cause of leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation.
Subcellular Location:
Mitochondrion matrix.
Similarity:
Belongs to the class-II aminoacyl-tRNA synthetase family.
Database links:Entrez Gene: 55157Human
Entrez Gene: 538772Cow
Entrez Gene: 226539Mouse
Entrez Gene: 304919Rat
GenBank: NM_018122.3Human
Omim: 610956Human
SwissProt: A6QPU5Cow
SwissProt: Q6PI48Human
SwissProt: Q8BIP0Mouse
SwissProt: Q3KRD0Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.