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货号： bs-1617R-PE-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-1617R-PE-Cy5.5
- 英文名称
- Anti-LI Cadherin/PE-Cy5.5
- 中文名称
- PE-Cy5.5标记的肝肠钙粘连蛋白抗体
- 别 名
- BILL-cadherin; LI-cadherin; CAD17_HUMAN; Cadherin 16; Cadherin 16, formerly; Cadherin 17; cadherin 17, LI cadherin (liver-intestine); cadherin, liver-intestine; Cadherin-17; CDH16; CDH16, formerly; Cdh17; FLJ26931; Formerly Cadherin 16; Formerly CDH16; HPT 1; HPT-1 cadherin; human intestinal peptide-associated transporter HPT-1; human peptide transporter 1; Intestinal peptide-associated transporter HPT 1; Intestinal peptide-associated transporter HPT-1; LI-cadherin; Liver Cadherin; liver intestine cadherin; Liver-intestine cadherin.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 免疫学 细胞骨架
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 90kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human LI-cadherin
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.
Function:
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport.
Subcellular Location:
Cell membrane; Single-pass type I membrane protein (Potential).
Tissue Specificity:
Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin.
Similarity:
Contains 7 cadherin domains.
Database links:Entrez Gene: 1015 Human
Omim: 603017 Human
SwissProt: Q12864 Human
Unigene: 591853 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肝肠钙粘连蛋白是钙粘连蛋白超家族中的特殊一员,在结构上与经典Ⅰ型钙粘连蛋白有所不同而被划分为经典钙粘连蛋白的变异体，主要用于消化道肿瘤方面的研究。