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货号: bs-2453R-PE-Cy5.5 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-2453R-PE-Cy5.5
- 英文名称
- Anti-CCL17/PE-Cy5.5
- 中文名称
- PE-Cy5.5标记的胸腺活化调节趋化因子抗体
- 别 名
- TARC; CCL17; SCYA17; ABCD-2; C-C motif chemokine 17; A152E53; CC Chemokine TARC; CCL17; Chemokine CC Motif Ligand 17; MGC138271; MGC138273; Small Inducible Cytokine A17; Small Inducible Cytokine A17 Precursor; Small Inducible Cytokine Subfamily A (Cys Cys); Small Inducible Cytokine Subfamily A (Cys Cys) Member 17; T Cell Directed CC Chemokine; Thymus and activation regulated chemokine; CCL17_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 8kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CCL17
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. TARC displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. TARC binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.
Function:
Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4.
Subcellular Location:
Secreted.
Tissue Specificity:
Expressed at high levels in thymus and at low levels in the lung, colon and small intestine.
Post-translational modifications:
One major form (form long), and two minor forms (short chain and medium chain) are produced by differential signal peptide cleavage. The medium chain is about 30-fold less active than the long chain.
Similarity:
Belongs to the intercrine beta (chemokine CC) family.
Database links:Entrez Gene: 6361 Human
Entrez Gene: 20295 Mouse
Entrez Gene: 117518 Rat
Omim: 601520 Human
SwissProt: Q92583 Human
Unigene: 546294 Human
Unigene: 41988 Mouse
Unigene: 46679 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.