产品中心
当前位置：首页>产品中心Anti-MMP11/PE-Cy5.5
货号： bs-1853R-PE-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-1853R-PE-Cy5.5
- 英文名称
- Anti-MMP11/PE-Cy5.5
- 中文名称
- PE-Cy5.5标记的基质金属蛋白酶11抗体
- 别 名
- matrix metalloproteinase 11; Stromelysin-3; SL-3; Matrix metalloproteinase-11; MMP11; MMP 11; MMP-11; SL 3; SL3; ST 3; ST3; STMY 3; STMY3; Stromelysin 3; Stromelysin 3 precursor; Stromelysin III; Stromelysin3; StromelysinIII. MMP11_HUMAN; stromelysin-3 preproprotein.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 43/51kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MMP11
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMPs, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008].
Function:
May play an important role in the progression of epithelial malignancies.
Subunit:
Secreted, extracellular space, extracellular matrix (Probable).
Subcellular Location:
Secreted, extracellular space, extracellular matrix (Probable).
Tissue Specificity:
Specifically expressed in stromal cells of breast carcinomas.
Post-translational modifications:
The precursor is cleaved by a furin endopeptidase.
Similarity:
Belongs to the peptidase M10A family.
Contains 4 hemopexin-like domains.
Database links:Entrez Gene: 4320 Human
Entrez Gene: 17385 Mouse
Entrez Gene: 25481 Rat
Omim: 185261 Human
SwissProt: P24347 Human
SwissProt: Q02853 Mouse
SwissProt: Q499S5 Rat
Unigene: 143751 Human
Unigene: 4561 Mouse
Unigene: 11123 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.