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货号： bs-1855R-PE-Cy5.5 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-1855R-PE-Cy5.5
- 英文名称
- Anti-MMP15/PE-Cy5.5
- 中文名称
- PE-Cy5.5标记的基质金属蛋白酶-15抗体
- 别 名
- Matrix metalloproteinase-15; MMP 15; MMP-15; MMP15; Matrix metallopeptidase 15 membrane inserted; Matrix metalloproteinase 15 ; Membrane type 2 Matrix Metalloproteinase; Membrane type matrix metalloproteinase 2; MT MMP 2; MT2 MMP; MT2MMP; MTMMP 2; MTMMP2; SMCP 2; SMCP2; MMP15_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 免疫学 激酶和磷酸酶
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 61/76kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MMP15
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. [provided by RefSeq, Jul 2008].
Function:
Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A.
Subcellular Location:
Membrane; Single-pass type I membrane protein; Extracellular side.
Tissue Specificity:
Appeared to be synthesized preferentially in liver, placenta, testis, colon and intestine. Substantial amounts are also detected in pancreas, kidney, lung, heart and skeletal muscle.
Post-translational modifications:
The precursor is cleaved by a furin endopeptidase (By similarity).
Similarity:
Belongs to the peptidase M10A family.
Contains 4 hemopexin-like domains.
Database links:Entrez Gene: 4324 Human
Entrez Gene: 17388 Mouse
Omim: 602261 Human
SwissProt: P51511 Human
SwissProt: O54732 Mouse
Unigene: 80343 Human
Unigene: 217116 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.