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货号： bs-3906R 基本售价： 780.0 元 规格： 50ul
- 规格：50ul
- 价格：780.00元
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 规格价格
- 50ul/780元购买 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 50ul 100ul 200ul
- 研究领域
- 肿瘤 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 41kDa
- 细胞定位
- 细胞浆 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human HSD3B1:301-373/373
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
Subcellular Location:
Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Tissue Specificity:
Placenta and skin. Predominantly expressed in mammary gland tissue.
Similarity:
Belongs to the 3-beta-HSD family.
SWISS:
P14060
Gene ID:
3283
Database links:Entrez Gene: 3283 Human
Entrez Gene: 3284 Human
Entrez Gene: 15492 Mouse
Entrez Gene: 15494 Mouse
Entrez Gene: 29632 Rat
Entrez Gene: 360348 Rat
Entrez Gene: 682974 Rat
Omim: 109715 Human
SwissProt: P14060 Human
SwissProt: P26439 Human
SwissProt: O35469 Mouse
SwissProt: P24815 Mouse
SwissProt: P26149 Mouse
SwissProt: P26150 Mouse
SwissProt: P22071 Rat
SwissProt: P22072 Rat
SwissProt: Q5FVK0 Rat
SwissProt: Q62878 Rat
Unigene: 364941 Human
Unigene: 654399 Human
Unigene: 140811 Mouse
Unigene: 14435 Mouse
Unigene: 158717 Mouse
Unigene: 482364 Mouse
Unigene: 109394 Rat
Unigene: 128814 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
HSD3B1属于滋养层细胞标记物（也包括hPL、hCG、Mel-CAN、p63、HLA—G、CK18和inhibin-α） 在很多肿瘤及正常内分泌组织中表达也很高。
- 产品图片
Paraformaldehyde-fixed, paraffin embedded (Rat liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (HSD3B1) Polyclonal Antibody, Unconjugated (bs-3906R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Rat kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (HSD3B1) Polyclonal Antibody, Unconjugated (bs-3906R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.